The Safety of the Renault Megane RS are as follow:
| Variants | 2019 Renault Megane RS 280 Cup MT | 2019 Renault Megane RS 280 Cup EDC Auto | 2015 Renault Megane RS 265 Cup |
| Euro NCAP Rating | 10 | ||
| ASEAN NCAP Rating | 0 | ||
| Airbags | 6 | 6 | 6 |
| Driver/Front Passenger Seat Airbags | Y/Y | Y/Y | Y/Y |
| Front/Rear Side Airbags | Y/Y | Y/Y | - |
| Front/Rear Curtain Airbags | Y/Y | Y/Y | Y |
| Knee Airbags | |||
| Rear Airbags | Y | Y | |
| Airbag Disable Function | Y | ||
| Seatbelt Reminder | Front Seats Only | ||
| Autonomous Emergency Braking | Y | Y | |
| Lane-keeping Alert | |||
| Blind Spot Info System | |||
| Collision Warning | |||
| ABS/EBD | Y | Y | |
| Electronic Stability Control(ESC) | Y | Y | |
| Child Safety Lock | |||
| ISOFIX | |||
| Security Alarm | |||
| Immobilizer |
