The Safety of the Lexus LC are as follow:
| Variants | 2018 Lexus LC LC 500 |
| Euro NCAP Rating | 0 |
| ASEAN NCAP Rating | 0 |
| Airbags | 8 |
| Driver/Front Passenger Seat Airbags | Y/Y |
| Front/Rear Side Airbags | - |
| Front/Rear Curtain Airbags | Y/Y |
| Knee Airbags | Front Knee |
| Rear Airbags | |
| Airbag Disable Function | Y |
| Seatbelt Reminder | For All Seats |
| Autonomous Emergency Braking | - |
| Lane-keeping Alert | N |
| Blind Spot Info System | Y |
| Collision Warning | - |
| ABS/EBD | Y |
| Electronic Stability Control(ESC) | Y |
| Child Safety Lock | - |
| ISOFIX | Y |
| Security Alarm | Y |
| Immobilizer | Y |
