The Safety of the Ford S-MAX are as follow:
| Variants | 2017 Ford S-MAX 2.0 EcoBoost | 2018 Ford S-Max 2.0L EcoBoost |
| Euro NCAP Rating | 10 | |
| ASEAN NCAP Rating | None | |
| Airbags | 7 | |
| Driver/Front Passenger Seat Airbags | Y/Y | Y/Y |
| Front/Rear Side Airbags | Y/N | Y/Y |
| Front/Rear Curtain Airbags | Y/Y | Y/Y |
| Knee Airbags | Driver Knee | |
| Rear Airbags | Y | |
| Airbag Disable Function | Y | Y |
| Seatbelt Reminder | All Seats | |
| Autonomous Emergency Braking | Y | |
| Lane-keeping Alert | Y | |
| Blind Spot Info System | Y | |
| Collision Warning | ||
| ABS/EBD | Y | |
| Electronic Stability Control(ESC) | Y | |
| Child Safety Lock | Manual for Rear Doors | |
| ISOFIX | Y | |
| Security Alarm | Y | |
| Immobilizer | Y |
