The Safety of the Mercedes-Benz AMG GT are as follow:
| Variants | 2019 Mercedes-Benz AMG GT C | 2019 Mercedes-Benz AMG GT R | 2018 Mercedes-Benz AMG GT C | 2018 Mercedes-Benz AMG GT R | 2018 Mercedes-Benz AMG GT S |
| Euro NCAP Rating | 0 | 0 | None | ||
| ASEAN NCAP Rating | 0 | 0 | None | ||
| Airbags | 8 | 8 | 8 | ||
| Driver/Front Passenger Seat Airbags | Y/Y | Y/Y | Y/Y | ||
| Front/Rear Side Airbags | - | - | - | ||
| Front/Rear Curtain Airbags | Y | Y | Y | ||
| Knee Airbags | Front Knee | Front Knee | Front Knee | ||
| Rear Airbags | |||||
| Airbag Disable Function | |||||
| Seatbelt Reminder | For All Seats | For All Seats | For All Seats | ||
| Autonomous Emergency Braking | Y | Y | Y | Y | Y |
| Lane-keeping Alert | Y | Y | N | N | N |
| Blind Spot Info System | Y | Y | - | - | - |
| Collision Warning | Y | Y | Y | ||
| ABS/EBD | Y | Y | Y | ||
| Electronic Stability Control(ESC) | Y | Y | Y | ||
| Child Safety Lock | - | - | - | ||
| ISOFIX | - | - | - | ||
| Security Alarm | Y | Y | |||
| Immobilizer | Y | Y | Y |
