The Safety of the Mazda 6 Sedan are as follow:
| Variants | 2018 Mazda 6 Sedan 2.0 SkyActiv-G with G-Vectoring Control | 2018 Mazda 6 Sedan 2.2 SkyActiv-D with G-Vectoring Control | 2018 Mazda 6 Sedan 2.5 SkyActiv-G with G-Vectoring Control | 2019 Mazda 6 Sedan 2.0 | 2019 Mazda 6 Sedan 2.5 | 2019 Mazda 6 Sedan 2.2 SkyActiv-D |
| Euro NCAP Rating | 10 | 10 | 10 | |||
| ASEAN NCAP Rating | None | 0 | None | |||
| Airbags | 6 | 6 | 6 | 6 | 6 | 6 |
| Driver/Front Passenger Seat Airbags | Y/Y | Y/Y | Y/Y | Y/Y | Y/Y | Y/Y |
| Front/Rear Side Airbags | Y/N | Y/N | Y/N | Y/N | Y/N | Y/N |
| Front/Rear Curtain Airbags | Y/Y | Y/Y | Y/Y | Y/Y | Y/Y | Y/Y |
| Knee Airbags | ||||||
| Rear Airbags | ||||||
| Airbag Disable Function | N | N | N | |||
| Seatbelt Reminder | For All Seats | For All Seats | For All Seats | For All Seats | For All Seats | For All Seats |
| Autonomous Emergency Braking | Y | Y | N | N | N | |
| Lane-keeping Alert | N | N | N | N | N | |
| Blind Spot Info System | Y | Y | ||||
| Collision Warning | Y | Y | N | N | Y | |
| ABS/EBD | Y | Y | Y | Y | Y | |
| Electronic Stability Control(ESC) | Y | Y | Y | |||
| Child Safety Lock | Manual for rear doors | Manual for rear doors | Manual for rear doors | Y | Y | Y |
| ISOFIX | Y | Y | Y | Y | Y | |
| Security Alarm | Y | Y | Y | Y | Y | |
| Immobilizer | Y | Y | Y |
